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Cat Number: API865363935

IslatravirMK-8591

CAS Number

865363-93-5

Description

Islatravir (MK-8591) is an effective anti-HIV-1 agent. It acts as a nucleoside reverse transcriptase inhibitor (EC50s: 0.068 nM, 3.1 nM, and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively).

Molecular Formula

C12H12FN5O3

Molecular Weight

293.25

Smiles

NC1NC(F)NC2N(CNC12)[C@H]1C[C@H](O)[C@@](CO)(O1)C#C

Purity

0.9877

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

H2O: 3 mg/mL (10.23 mM), Sonication and heating to 60℃ are recommended.DMSO: 100 mg/mL (341.01 mM), Sonication is recommended.

Relative Density

1.72 (Predicted)

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