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Cat Number: API870281826

IdelalisibGS-1101, CAL-101

CAS Number

870281-82-6

Description

Idelalisib (GS-1101) is a small molecule inhibitor of the PI3K catalytic subunit p110δ (IC50: 2.5 nM). The selectivity for p110δ is 40- to 300-fold than p110α/β/γ.

Molecular Formula

C22H18FN7O

Molecular Weight

415.42

Smiles

[C@H](NC1=C2C(N=CN2)=NC=N1)(CC)C=3N(C(=O)C=4C(N3)=CC=CC4F)C5=CC=CC=C5

Purity

0.9994

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

H2O: InsolubleEthanol: 22 mg/mL (53 mM)DMSO: 50 mg/mL (120.36 mM)

Relative Density

1.47

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