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Cat Number: API66852548

Halobetasol propionateHalobetasol Propionate, Ulobetasol propionate, BMY-30056, CGP-14458

CAS Number

66852-54-8

Description

Halobetasol propionate (BMY-30056) is the propionate salt form of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities. Halobetasol, a topical steroid, diffuses across cell membranes to interact with cytoplasmic corticosteroid receptors located in both the dermal and intradermal cells, thereby activating gene expression of anti-inflammatory proteins mediated via corticosteroid receptor response element.

Molecular Formula

C25H31ClF2O5

Molecular Weight

484.96

Smiles

CCC(=O)O[C@@]1([C@@H](C)CC2C3C[C@H](F)C4=CC(=O)C=CC4(C)[C@@]3(F)C(O)CC12C)C(=O)CCl

Purity

0.9985

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

H2O: < 1 mg/mL (insoluble or slightly soluble)Ethanol: 36 mg/mL (74.2 mM)DMSO: 90 mg/mL (185.6 mM)