Description
GSK9027 (GR agonist 23a) is a nonsteroidal glucocorticoid receptor (GR) agonist.GSK9027 is a partial agonist on the 2×GRE reporter gene compared to dexamethasone and is less active than dexamethasone activity.
Molecular Formula
C27H19F4N3O2S
Smiles
FC1=CC=C(N2C=3C(=CC(=CC3)C4=C(C(F)(F)F)C=C(NS(CC5=CC=CC=C5)(=O)=O)C=C4)C=N2)C=C1
Storage
Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.
Solubility Information
DMSO: 60 mg/mL (114.17 mM), Sonication is recommended.