Cat Number: API95058814

GemcitabineNSC 613327, LY188011

APIs
CAS Number
95058-81-4
Description
Gemcitabine (LY188011) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis. Gemcitabine has antitumor and antimetabolic activities. Gemcitabine induces autophagy and apoptosis.
Molecular Formula
C9H11F2N3O4
Molecular Weight
263.2
Smiles
NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)C1(F)F
Purity
1
Storage
Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.
Solubility Information
H2O: 6.25 mg/mL (23.75 mM), Sonication is recommended.DMSO: 125mg/mL (474.92 mM), Sonication is recommended.Ethanol: 12.5 mg/mL (47.49 mM), Sonication is recommended.5% DMSO+95% Saline: 0.75 mg/mL (2.85 mM), In vivo: Please add co-solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately.
Relative Density
1.84 (Predicted)
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