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Cat Number: API397864447

Fluticasone furoate

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CAS Number

397864-44-7

Synonyms

Veramyst, Allermist, Avamys, Fluticasone furoate

Description

Fluticasone furoate (Avamys) is a synthetic trifluorinated corticosteroid derived from fluticasone with a Kd of 0.3 nM. Fluticasone furoate has potent anti-inflammatory, anti-asthmatic activity, and low systemic exposure. Fluticasone furoate can be used as a nasal spray for studies about allergic rhinitis treatment.

Molecular Formula

C27H29F3O6S

Molecular Weight

538.58

Smiles

[H][C@@]12C[C@@H](C)[C@](OC(=O)C3CCCO3)(C(=O)SCF)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C

Purity

0.9958

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

H2O: InsolubleDMSO: 95 mg/mL (176.39 mM), Sonication is recommended.