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Cat Number: API78755814

FlumazenilRo 15-1788

CAS Number

78755-81-4

Description

Flumazenil (Ro 15-1788) antagonizes the benzodiazepine binding site of the gamma-aminobutyric acid (GABA)/benzodiazepine receptor complex in the central nervous system (CNS), thereby preventing the chloride channel opening events and inhibiting neuronal hyperpolarization.

Molecular Formula

C15H14FN3O3

Molecular Weight

303.29

Smiles

CCOC(=O)C1NCN-2C1CN(C)C(=O)C1CC(F)CCC-21

Purity

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

DMSO: 11 mg/mL (36.27 mM), Sonication is recommended.H2O: < 1 mg/mL (insoluble or slightly soluble)Ethanol: < 1 mg/mL (insoluble or slightly soluble)

Relative Density