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Cat Number: API59973807

ExisulindSulindac sulfone, CP248

CAS Number

59973-80-7

Description

Exisulind (CP248) induces apoptosis through the activation of protein kinase G (PKG). Exisulind exhibits antineoplastic activity in solid tumour and haematological cancer cell lines and is an inhibitor of tumour growth in rodent models of colon, prostate, bladder, mammary and lung cancer.

Molecular Formula

C20H17FO4S

Molecular Weight

372.41

Smiles

CC1=C(CC(O)=O)C2CC(F)CCC2\C1=C/C1CCC(CC1)S(C)(=O)=O

Purity

0.9808

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

DMSO: 55 mg/mL (147.69 mM)