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Cat Number: API1051375199

Dolutegravir sodiumGSK1349572, GSK-1349572A

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APIs
CAS Number
1051375-19-9
Description
Dolutegravir sodium (GSK-1349572A) salt(DTG; GSK1349572) is an HIV integrase inhibitor(IC50: 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.
Molecular Formula
C20H18F2N3NaO5
Molecular Weight
441.36
Smiles
[Na+].C[C@@H]1CCO[C@H]2CN3CC(C(=O)NCC4CCC(F)CC4F)C(=O)C([O-])C3C(=O)N12
Purity
0.9974
Storage
Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.
Solubility Information
DMSO: 4.41 mg/mL (10 mM)
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