Dacomitinib hydratePF 299804, PF00299804, PF 00299804, PF-00299804, PF299804, PF-299804
Description
Dacomitinib hydrate (PF 299804) is a highly selective and second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor family of tyrosine kinases.
Molecular Formula
C24H27ClFN5O3
Smiles
O.COC1CC2NCNC(NC3CCC(F)C(Cl)C3)C2CC1NC(=O)\C=C\CN1CCCCC1
Storage
Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.
Solubility Information
DMSO: 55 mg/ml (112.71 mM)