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Cat Number: API1195768069

Dabrafenib MesylateGSK2118436 Mesylate, GSK 2118436B

CAS Number

1195768-06-9

Description

Dabrafenib Mesylate (GSK2118436 Mesylate) is a B-Raf inhibitor(IC50s of 0.6 and 5.0 nM for RafV600E and c-Raf, respectively).

Molecular Formula

C24H24F3N5O5S3

Molecular Weight

615.67

Smiles

CS(O)(=O)=O.CC(C)(C)C1NC(C(s1)-C1CCNC(N)N1)-C1CCCC(NS(=O)(=O)C2C(F)CCCC2F)C1F

Purity

0.9962

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

DMSO: 45 mg/mL (73.09 mM)

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