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Cat Number: API1415560698

Crizotinib hydrochloridePF-02341066 hydrochloride

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APIs
CAS Number
1415560-69-8
Description
Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met, with IC50 values of 20 nM and 8 nM, respectively.
Molecular Formula
C21H23Cl3FN5O
Molecular Weight
486.8
Smiles
Cl.C[C@@H](OC1CC(CNC1N)-C1CNN(C1)C1CCNCC1)C1C(Cl)CCC(F)C1Cl
Purity
0.9967
Storage
Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.
Solubility Information
DMSO: 10 mg/mL (20.54 mM), Sonication is recommended.H2O: 50 mg/mL (102.71 mM), Sonication is recommended.
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