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Cat Number: API123318821

ClofarabineClofarex, Evoltra, Clolar

CAS Number

123318-82-1

Description

Clofarabine (Clofarex)m, a second generation purine nucleoside analog with antineoplastic activity, inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase.

Molecular Formula

C10H11ClFN5O3

Molecular Weight

303.68

Smiles

NC1NC(Cl)NC2N(CNC12)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1F

Purity

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

DMSO: 40 mg/mL (131.72 mM), Sonication is recommended.

Relative Density

2.12

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