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Cat Number: API364782343

Cinacalcet hydrochloride

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CAS Number

364782-34-3

Synonyms

Cinacalcet HCl, AMG-073 hydrochloride, AMG-073 HCl

Description

Cinacalcet hydrochloride (AMG-073 hydrochloride) is a naphthalene derivative and calcimimetic agent that enhances the sensitivity of parathyroid gland calcium-sensing receptors to serum calcium, thereby reducing parathyroid hormone secretion and decreasing serum calcium in the treatment of parathyroid diseases.

Molecular Formula

C22H23ClF3N

Molecular Weight

393.87

Smiles

C[C@H](C1CCCC2CCCCC12)NCCCC1CC(CCC1)C(F)(F)F.Cl

Purity

0.9994

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

DMSO: 50 mg/mL (126.95 mM)