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Cat Number: API1140909483

Cabozantinib S-malateXL184, Cabozantinib Malate, Cabozantinib

CAS Number

1140909-48-3

Description

Cabozantinib S-malate (XL184) is the s-malate salt form of cabozantinib, an orally bioavailable, small molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity.

Molecular Formula

C32H30FN3O10

Molecular Weight

635.59

Smiles

O[C@@H](CC(O)=O)C(O)=O.COC1CC2NCCC(OC3CCC(NC(=O)C4(CC4)C(=O)NC4CCC(F)CC4)CC3)C2CC1OC

Purity

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

H2O: < 1 mg/mL (insoluble or slightly soluble)DMSO: 16.67 mg/mL (26.22 mM), Sonication is recommended.Ethanol: < 1 mg/mL (insoluble or slightly soluble)

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