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Cat Number: API1051375100

CabotegravirGSK744, GSK-1265744, S GSK1265744

CAS Number

1051375-10-0

Description

Cabotegravir (S/GSK1265744) (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (IC50: 3.0 nM).

Molecular Formula

C19H17F2N3O5

Molecular Weight

405.35

Smiles

O=C1C=2N(C[C@@]3(N1[C@@H](C)CO3)[H])C=C(C(NCC4=C(F)C=C(F)C=C4)=O)C(=O)C2O

Purity

0.9992

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

DMSO: ＜1 mg/mL (insoluble or slightly soluble)H2O: < 1 mg/mL (insoluble or slightly soluble)Ethanol: < 1 mg/mL (insoluble or slightly soluble)

Relative Density

1.57 (Predicted)

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