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Cat Number: API2204245485

BamocaftorVX-659

CAS Number

2204245-48-5

Description

Bamocaftor is a CFTR channel (DeltaF508-CFTR mutation) corrector for CF transmembrane conductance regulators designed to restore F508del-CFTR protein function. Combined use of tezacaftor and VX-561 for the treatment of cystic fibrosis patients with F508del/MF.

Molecular Formula

C28H32F3N5O4S

Molecular Weight

591.65

Smiles

C[C@@H]1CN(C2NC(CCC2C(=O)NS(=O)(=O)C2CCCCC2)-N2CCC(OCCC3(CC3)C(F)(F)F)N2)C(C)(C)C1

Purity

0.9985

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

DMSO: 18.33 mg/mL (30.99 mM)