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Cat Number: API1231930827

Abemaciclib methanesulfonateabemaciclib mesylate, LY2835219, LY2835219 mesylate, LY2835219 (methanesulfonate)

CAS Number

1231930-82-7

Description

Abemaciclib methanesulfonate (LY2835219) is a specific and effective inhibitor of CDK4(IC50=2 nM) and CDK6(IC50=10 nM).

Molecular Formula

C27H32F2N8·CH4O3S

Molecular Weight

602.7

Smiles

CS(O)(=O)=O.CCN1CCN(CC2CCC(NC3NCC(F)C(N3)-C3CC(F)C4NC(C)N(C(C)C)C4C3)NC2)CC1

Purity

0.9944

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

H2O: 45 mg/mL (74.7 mM)DMSO: 6.03 mg/mL (10 mM), Sonication is recommended.Ethanol: 23 mg/mL (38.2 mM)

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