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Cat Number: API51218

5-FluorouracilNSC 19893, Fluorouracil, 5-FU, 5-Fluoracil

CAS Number

51-21-8

Description

5-Fluorouracil (5-FU) is a uracil analog and inhibitor of DNA synthesis, exhibiting antitumor activity by affecting pyrimidine synthesis through thymidylate synthase inhibition; it induces apoptosis and autophagy.

Molecular Formula

C4H3FN2O2

Molecular Weight

130.08

Smiles

FC1=CNC(=O)NC1=O

Purity

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

10% DMSO+90% Saline: 1.3 mg/mL (9.99 mM), In vivo: Please add co-solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately.Ethanol: 1.3 mg/mL (10 mM)H2O: 10 mg/mL (76.8 mM), Heating at 50℃ is recommended.DMSO: 18.33 mg/mL (140.94 mM)

Relative Density

1.53

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