5-Fluorouracil-13C,15N25-Fluorouracil-13C,15N2

1189423-58-2

5-Fluorouracil-13C,15N2 is intended for use as an internal standard for the quantification of 5-flurouracil by GC- or LC-MS. 5-Fluorouracil is a pyrimidine analog that irreversibly inhibits thymidylate synthase, blocking the synthesis of thymidine which is required for DNA synthesis. Intracellular metabolites of 5-fluorouracil exert cytotoxic effects by either inhibiting thymidylate synthetase, or through incorporation into RNA and DNA, ultimately initiating apoptosis.

C4H3FN2O2

133.057

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

DMSO: Slightly solubleMethanol: Slightly soluble