Synonyms
Interleukin 7;IL7; IL-7; IL-7interleukin-7; interleukin 7; Lymphopoietin-1; PBGF
Description
Interleukin 7 (IL-7) is a cytokine involved in the regulation of immune cell development and survival, including T and B lymphocytes. It is produced by stromal cells, such as fibroblasts and bone marrow stromal cells. Dysregulation of IL-7 signaling has been implicated in autoimmune diseases and cancer.
Molecular Weight
The protein has a predicted MW of 19.34 kDa. And it migrates as 25-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity
> 95% as determined by SDS-PAGE.
Endotoxin
< 0.1 EU per 1μg of the protein
Formulation
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).