CXCL9-3

C-X-C motif chemokine 9, CXCL9, Gamma-interferon-induced Monokine, Humig, MIG, Small-inducible Cytokine B9

Chemokine CXCL9 is a member of the CXC family and has an important role in the chemotaxis of immune cells. The mouse CXCL9 shares 75% and 88% a.a. sequence identity with human and rat CXCL9. Accumulated experimental evidence supports that monokine induced by interferon (IFN)-gamma (CXCL9), a member of CXC chemokine family and known to attract CXCR3- (A and B) T lymphocytes, is involved in the pathogenesis of physiologic diseases during their initiation and their maintenance. It is a cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response and chemotactic for activated T-cells.

Approximately 11.9 kDa.

Sterile Filtered White lyophilized (freeze-dried) powder.

>96% by SDS-PAGE and HPLC analyses.