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Crizotinib

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Cat Number

API877399525

CAS Number

877399-52-5

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Product Detail

CAS Number

877399-52-5

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Description

Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinase inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptors.

Molecular Formula

C21H22Cl2FN5O

Molecular Weight

450.34

Smiles

O([C@H](C)C1=C(Cl)C(F)=CC=C1Cl)C2=CC(C3=CN(N=C3)C4CCNCC4)=CN=C2N

Relative Density

1.475

Purity

0.9987

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