N-BOC-D-CYCLOHEXYLGLYCINOL

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Cat Number

INT188348007

CAS Number

188348-00-7

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Product Detail Description Customer Q&A

CAS Number

188348-00-7

Storage

2-8℃

Synonyms

BOC-D-CYCLOHEXYLGLYCINOL;BOC-D-CHG-OL

Molecular Formula

C13H25NO3

Molecular Weight

243.34

Smiles

CC(C)(C)OC(=O)N[C@@H](CO)C1CCCCC1

Appearance

White to off-white solid

Relative Density

1.037

pKa

12.07

General Description

N-BOC-D-CYCLOHEXYLGLYCINOL is a chiral amino alcohol derivative featuring a cyclohexyl group at the alpha position and a tert-butoxycarbonyl protecting group on the amine. It is the reduced alcohol form of N-Boc-D-cyclohexylglycine.

Mechanism of Action

It acts as a chiral scaffold for organic synthesis. The presence of both a protected amine and a primary alcohol allows for diverse chemical transformations, including the synthesis of complex chiral ligands, catalysts, and cyclic amino alcohol derivatives.

Application

It is primarily used in medicinal chemistry for the development of protease inhibitors and as a chiral intermediate for the synthesis of bioactive compounds requiring a cyclohexyl moiety.