Entecavir Monohydrate

Inquiry

Cat Number

API209216239

CAS Number

209216-23-9

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Product Detail

CAS Number

209216-23-9

EINECS

606-668-5

Synonyms

Entecavir hydrate entecavir monohydrate Entecavir (monohydrate) Entecavir hydrate (JAN)

Description

A synthetic analogue of 2'-deoxyguanosine, entecavir is a nucleoside reverse transcriptase inhibitor with selective antiviral activity against hepatitis B virus. It is phosphorylated intracellularly to the active triphosphate form, which competes with deoxyguanosine triphosphate, the natural substrate of hepatitis B virus reverse transcriptase, inhibiting every stage of the enzyme's activity, although it has no activity against HIV. Enteclavir is used for the treatment of chronic hepatitis B. It has a role as an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor and an antiviral drug.

Molecular Formula

C12H17N5O4

Molecular Weight

295.29

Appearance

White Powder

Melting Point

31℃

Boiling Point

661.4℃ at 760 mmHg

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