Dimethyl Sulfoxide (DMSO)

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Cat Number

CHE67685

CAS Number

67-68-5

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CAS Number

67-68-5

EINECS

200-664-3

Synonyms

DMSO

Molecular Formula

C2H6OS

Molecular Weight

78.13

Appearance

Colorless liquid

Melting Point

18.4 ℃

Boiling Point

189 ℃

Relative Density

1.1

pKa

General Description

Dimethyl sulfoxide (DMSO) is a sulfur-containing organic solvent that is commonly described as a "universal solvent" due to its broad solvating capability. It is a colorless, transparent liquid at room temperature and is one of the most polar aprotic solvents with a high boiling point and water miscibility and it can also dissolve in most organic solvents (such as alcohols, ethers, chloroform). Its dissolving power has made it the solvent of choice for many organic compounds, polymers, peptides, and many inorganic salts.

Application

Dimethyl sulfoxide is used in a wide variety of applications. Its primary use is as a solvent and reaction medium in chemical industries, a direct material and drug carrier/vehicle for pharmaceutical industries and a cryoprotectant in cell biology, which is used to freeze and store primary cells/cell lines, embryonic stem cells and hematopoietic stem cells safely.

Ultrasound-assisted DMSO method can make quick (<10 min) and controllable starch gel formations due to DMSO–water synergism. Medicinal herb Trichosanthes kirilowii pulp starch with good swelling properties was pre-dispersed in DMSO. Ultrasound helped molecular substitution and polymer chain entanglement to form starch gels. It is also tunable in viscosity (broad and accurate range) by modulating starch and DMSO concentrations. As DMSO is a green and biocompatible solvent with good solubilizing capability for many drugs and has skin penetration ability, gelation of starch was achieved in one step without the addition of a cross-linker or requiring any long time retrogradation process. This gel incorporated both hydrophilic (methotrexate) and hydrophobic (MoS2) actives and showed high adherence and transdermal capability. This method can be further used for developing psoriasis patches and surface modified hemodialysis membranes with a new option for personalized biomedical therapy.

Fig. 1 DMSO method for rapid starch gel preparation. (Pan X.; et al. 2025)

References

Pan X, et al. Ultrasound-assisted DMSO method for rapid starch gel preparation: process and biomedical applications. Chemical Engineering Journal, 2025: 166488.

Which regions do you ship to?

We serve major countries and regions globally, ensuring the reliable delivery of our chemical products.

What are the chemical properties of DMSO?

DMSO is a polar aprotic, low-toxicity solvent with a high-boiling point, excellent thermal stability, and miscible in water and most organic solvents.

Which industries do you supply DMSO for?

We cater to a wide range of industries with our DMSO, including pharmaceuticals, agrochemicals, polymers, and specialty chemicals.

Do you handle bulk industrial orders?

Yes, we support orders ranging from small-scale R&D to large-volume industrial production.

What is the purity of your DMSO?

We offer DMSO in various grades of purity, including high-purity pharmaceutical-grade suitable for sensitive applications.