Synonyms
HC14 Protein, Human; MCP-2 Protein, Human; MCP2 Protein, Human; SCYA10 Protein, Human; SCYA8 Protein, Human
Description
CCL8, also known as monocyte chemotactic protein 2 (MCP-2), is belonging to the CC chemokine family. It is encoded by the gene CCL8. MCP-2 has two homogeneous MCP-1 (CCL2) and MCP-3 (CCL7). These three MCPs were found by IL-1-beta triggered human MG-63 osteosarcoma cells. CCL8 shares 62 % amino acid sequence identity with MCP-1, and shares 58 % amino acid sequence identity with MCP-2. CCL8 has chemotactic function for monocytes, eosinophils and neutrophils. In addition, it can also chemoattract activated NK cells.
Molecular Weight
Approximately 8.9 kDa.
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Purity
> 96 % by SDS-PAGE and HPLC analyses.