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Binimetinib

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Cat Number

API606143899

CAS Number

606143-89-9

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Product Detail

CAS Number

606143-89-9

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Description

Binimetinib (ARRY-162) is a MEK1/2 inhibitor (IC50=12 nM) with selective and oral activity. Binimetinib has antitumor activity for the treatment of metastatic melanoma that cannot be resected or has a BRAF V600E or V600K mutation.

Molecular Formula

C17H15BrF2N4O3

Molecular Weight

441.23

Smiles

CN1CNC2C(F)C(NC3CCC(Br)CC3F)C(CC12)C(=O)NOCCO

Relative Density

1.67

Purity

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