Salvianolic acid A

96574-01-5

Room temperature

SALVIANOLIC ACID Dan Phenolic Acid A (R)-3-(3,4-Dihydroxyphenyl)-2-(((E)-3-(2-((E)-3,4-dihydroxystyryl)-3,4-dihydroxyphenyl)acryloyl)oxy)propanoic acid

Salvianolic acid A is extracted from the root of Salvia miltiorrhiza Bge. It has anti-oxidative capabilities. It can reverse paclitaxel resistance through suppressing transgelin 2 expression by mechanisms involving attenuation of PI3 K/Akt pathway activation and ABC transporter up-regulation. It has inhibitory effect on Cu2+ mediated human LDL oxidation through chelating Cu2+ and scavenging free radicals. It inhibited proliferation, caused cell cycle arrest at the S phase, and induced apoptosis dose dependently to the two kinds of cancer cells. It positively regulates PTEN protein level and inhibits growth of A549 lung cancer cells.

C26H22O10

494.4

Powder

HPLC≥98%