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Regorafénib N-oxyde (M2)

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Cat Number

API835621119

CAS Number

835621-11-9

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Product Detail

CAS Number

835621-11-9

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Description

Regorafénib N-oxyde M2 is an active metabolite of Regorafenib, a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, RET, Kit, and Raf-1 (IC50s: 13/4.2/46, 1.5, 22, 7, and 2.5 nM).

Molecular Formula

C21H15ClF4N4O4

Molecular Weight

498.81

Smiles

CNC(=O)C1CC(OC2CCC(NC(=O)NC3CCC(Cl)C(C3)C(F)(F)F)C(F)C2)CC[N+]1[O-]

Relative Density

1.49 (Predicted)

Purity

0.9948

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