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Cat Number: API835621119

Regorafénib N-oxyde (M2)

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APIs
CAS Number
835621-11-9
Description
Regorafénib N-oxyde M2 is an active metabolite of Regorafenib, a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, RET, Kit, and Raf-1 (IC50s: 13/4.2/46, 1.5, 22, 7, and 2.5 nM).
Molecular Formula
C21H15ClF4N4O4
Molecular Weight
498.81
Smiles
CNC(=O)C1CC(OC2CCC(NC(=O)NC3CCC(Cl)C(C3)C(F)(F)F)C(F)C2)CC[N+]1[O-]
Purity
0.9948
Storage
Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.
Solubility Information
DMSO: Slightly soluble
Relative Density
1.49 (Predicted)
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