PSA/Kallikrein-3

Cat Number
92550ES

For research use only. We do not supply to patients.

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Synonyms
APS seminin, hK3, Kallikrein 3, KLK2A1, KLK3, P-30 antigen, PSA
Description
Kallikrein 3, commonly known as prostate specific antigen (PSA), is a serine protease of the human tissue Kallikrein gene family. The human tissue kallikrein (KLK) gene family contains 15 members that play important roles in cancer. Kallikrein-3, called prostate specific antigen (PSA), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is secreted by the epithelial cells of the prostate gland, hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum. PSA is an established tumor marker that aids in the diagnosis, staging, and follow up of prostate cancer.
Molecular Weight
Approximately 26.1 kDa.
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Purity
>95% by SDS-PAGE and HPLC analyses.
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